LC-MS/MS Method for the Determination of 21 Opiates and Opiate Derivatives in Urine
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Determination of benzodiazepines in urine via benzophenone derivatives using liquid chromatography-tandem mass spectrometry.
The aim of this study was to validate a new method for determining benzodiazepines in urine via their benzophenone derivatives, based on liquid chromatography-tandem mass spectrometry (LC-MS/MS). Selected benzodiazepines were analysed after acid hydrolysis of urine and extraction by ethyl acetate in the presence of an internal standard. Samples were analysed using electrospray ionization LC-MS/...
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